Uterine Rejuvenation (PRP) treatment
A key component of implantation and pregnancy is adequate endometrial thickness. Furthermore, reproductive success rates following assisted reproductive technology (ART) have been found to be negatively impacted by thin endometrium. Numerous therapeutic approaches have been proposed to increase endometrial thickness and, consequently, endometrial receptivity.
One new method for treating thin endometrium is intrauterine injection of platelet-rich plasma (PRP). Thus far, a number of research have shown how successful this method is. Autologous blood plasma that has been enhanced with platelets at a ratio of roughly four to five times that of circulating blood is known as PRP. PRP contains a lot of growth factors and cytokines that can promote regeneration and proliferation.
What Is Uterine Rejuvenation
Uterine rejuvenation is an innovative regenerative medicine approach designed to support the health and function of the endometrium, the inner lining of the uterus. A healthy endometrium plays a fundamental role in successful embryo implantation and the establishment of pregnancy.
The treatment aims to improve the biological environment of the uterus by stimulating the body’s natural repair mechanisms. Depending on the patient’s needs, regenerative therapies such as Platelet-Rich Plasma (PRP), exosome therapy, or other advanced regenerative techniques may be incorporated into a personalized treatment plan.
At Chania Fertility Unit, uterine rejuvenation is offered as part of a comprehensive fertility program that combines regenerative medicine with advanced assisted reproductive technologies, including IVF and ICSI.
Benefits of Uterine Rejuvenation
Uterine rejuvenation may be considered for women who have experienced recurrent implantation failure, thin endometrium, previous unsuccessful IVF cycles, or reduced endometrial receptivity. It may also be appropriate for selected patients with uterine changes associated with age or previous uterine procedures.
The goal is to optimize the uterine environment before embryo transfer by encouraging endometrial regeneration and improving tissue quality. Every patient undergoes a comprehensive fertility assessment to determine whether regenerative treatment is appropriate for her individual circumstances.
Because each fertility journey is unique, treatment recommendations are based on medical history, ultrasound findings, hormonal evaluation, and previous reproductive outcomes.
How Uterine Rejuvenation Works
Regenerative therapies used for uterine rejuvenation are designed to support cellular communication, tissue repair, and blood vessel formation within the endometrium. These biological processes may contribute to improved tissue regeneration and a healthier uterine environment.
By promoting endometrial repair and enhancing local vascularization, uterine rejuvenation may help prepare the uterus for embryo implantation in selected patients. Current research continues to investigate the role of regenerative medicine in improving endometrial health and reproductive outcomes.
Although early clinical findings are encouraging, treatment responses vary among individuals, and no regenerative therapy can guarantee implantation or pregnancy.
